Addresses AP® Chemistry Big Idea 2 and Learning Objective 2.10. In the guided activity, students identify 3 food dyes in powdered drink mixes using paper chromatography and identify the components in plant pigment using thin-layer chromatography. In the inquiry activity, students design an experiment to separate food dyes in drink mixes and must select the proper mobile and stationary phases to effect an efficient separation. Materials are sufficient for 30 students working in teams of 3.